Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIEZO1 | Q92508 | 5/20 | 0.74 |
| ▸ | TERT | O14746 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23195706 | 0.87 | PIEZO1 (0.81) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL6490578 | 0.85 | PIEZO1 (1.00) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL23195699 | 0.83 | PIEZO1 (0.78) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL23195769 | 0.82 | PIEZO1 (0.73) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL31520562 | 0.82 | PIEZO1 (0.73) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL31520557 | 0.82 | PIEZO1 (0.73) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL23195352 | 0.80 | PIEZO1 (0.69) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL23195361 | 0.79 | PIEZO1 (0.83) | PIEZO1TERTALDH1A1ATMHSD17B10 | |
| SCHEMBL23195738 | 0.78 | PIEZO1 (0.67) | PIEZO1TERTALDH1A1ATMMEN1 | |
| SCHEMBL6490858 | 0.75 | TERT (0.77) | PIEZO1TERTALDH1A1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067943-A1 | PIEZO1 AGONISTS FOR THE PROMOTION OF BONE FORMATION | BIOVENTURES, LLC (US) | 2021-04-08 | — | — | WO | disclosed |