SCHEMBL23196136

SCHEMBL23196136

Cc1nc(-c2ccc(C(=O)NCC(c3cc4c(c(-c5ccc(F)cc5)n3)OC[C@]4(C)C(N)=O)C(F)(F)F)cc2OC2CC2)co1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UGCG Q16739 1/20 0.31
SLC5A7 Q9GZV3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23196269 1.00 UGCG (0.31) UGCGSLC5A7
SCHEMBL23195595 0.92 GABRA5 (0.31) UGCGSLC5A7
SCHEMBL23196124 0.90 NAMPT (0.33) SLC5A7
SCHEMBL23196125 0.90 SLC5A7 (0.32) UGCGSLC5A7
SCHEMBL23195997 0.89 AR (0.31) SLC5A7
SCHEMBL23196126 0.88 ROCK2 (0.34) SLC5A7
SCHEMBL23196108 0.87 KLKB1 (0.36) SLC5A7
SCHEMBL24985871 0.86 GABRA5 (0.30) UGCG
SCHEMBL24988037 0.86 GABRA5 (0.30) UGCG
SCHEMBL23195904 0.85 SLC5A7 (0.31) SLC5A7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021066922-A1 ANTIVIRAL HETEROCYCLIC COMPOUNDS ENANTA PHARMACEUTICALS, INC. (US) 2021-04-08 WO disclosed