Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | SLC5A7 | Q9GZV3 | 3/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | BCL9 | O00512 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196125 | 0.91 | SLC5A7 (0.32) | NAMPTSLC5A7ARALDH1A1SMN1; SMN2 | |
| SCHEMBL23195595 | 0.91 | GABRA5 (0.31) | GABRA5SLC5A7AR | |
| SCHEMBL23196126 | 0.90 | ROCK2 (0.34) | KLKB1SLC5A7ARALDH1A1SMN1; SMN2 | |
| SCHEMBL23196136 | 0.90 | UGCG (0.31) | SLC5A7 | |
| SCHEMBL23196269 | 0.90 | UGCG (0.31) | SLC5A7 | |
| SCHEMBL23195997 | 0.89 | AR (0.31) | SLC5A7AR | |
| SCHEMBL23196108 | 0.88 | KLKB1 (0.36) | KLKB1SLC5A7 | |
| SCHEMBL23195904 | 0.87 | SLC5A7 (0.31) | SLC5A7 | |
| SCHEMBL23195848 | 0.86 | PTK2 (0.33) | GABRA5SLC5A7ALDH1A1SMN1; SMN2BCL9 | |
| SCHEMBL26568540 | 0.86 | SLC5A7 (0.33) | NAMPTSLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066922-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARMACEUTICALS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |