Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL975118 | 0.73 | SRD5A2 (0.83) | MAPTALDH1A1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL10723714 | 0.73 | SRD5A2 (0.83) | MAPTALDH1A1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL418856 | 0.72 | ACHE (0.72) | MAPTALDH1A1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL10920493 | 0.72 | PDE4A (0.60) | MAPTALDH1A1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL14044077 | 0.70 | DAO (0.50) | ALDH1A1KMT2AL3MBTL1LMNAGAA | |
| SCHEMBL10559760 | 0.69 | ALDH1A1 (0.73) | MAPTALDH1A1TDP1L3MBTL1SRD5A2 | |
| SCHEMBL4808746 | 0.69 | PIK3C3 (0.65) | MAPTKMT2AL3MBTL1MEN1HPGD | |
| SCHEMBL1531253 | 0.69 | PIK3C3 (0.56) | MAPTALDH1A1TDP1KMT2ALMNA | |
| Water SCHEMBL28104393 | 0.69 | POLB (0.79) | MAPTALDH1A1TDP1KMT2AL3MBTL1 | |
| SCHEMBL6746532 | 0.68 | TDP1 (0.63) | MAPTALDH1A1TDP1L3MBTL1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |