Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | PPIB | P23284 | 1/20 | 0.31 |
| ▸ | PPIA | P62937 | 1/20 | 0.31 |
| ▸ | PPID | Q08752 | 1/20 | 0.31 |
| ▸ | PPIG | Q13427 | 1/20 | 0.31 |
| ▸ | NR1D1 | P20393 | 3/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054669 | 0.94 | PPIB (0.32) | ACACBPPIBPPIAPPIDPPIG | |
| SCHEMBL3748687 | 0.85 | NR1D1 (0.36) | ACACBPPIBPPIAPPIDPPIG | |
| SCHEMBL25983031 | 0.83 | TOP2A (0.33) | PPIBPPIAPPIDPPIGSLC22A2 | |
| SCHEMBL12761956 | 0.83 | NR1D1 (0.34) | ACACBPPIBPPIAPPIDPPIG | |
| SCHEMBL9924674 | 0.81 | NR1D1 (0.33) | ACACBNR1D1NR1H3 | |
| SCHEMBL13375696 | 0.79 | NR1D1 (0.33) | ACACBNR1D1NR1H3CYP2C19 | |
| SCHEMBL5033940 | 0.78 | NR1D1 (0.36) | NR1D1NR1H3 | |
| SCHEMBL23197894 | 0.78 | KDM4E (0.30) | — | |
| SCHEMBL7801949 | 0.78 | — | — | |
| SCHEMBL5374479 | 0.76 | CTSS (0.38) | ACACBNR1D1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067738-A1 | DEVELOPMENT OF IMAGING AND THERAPEUTIC GLUCOSE ANALOGUES FOR SODIUM DEPENDENT GLUCOSE TRANSPORTERS | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-04-08 | — | — | WO | disclosed |