Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1D1 | P20393 | 4/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3748687 | 0.88 | NR1D1 (0.36) | NR1D1NR1H3CTSSCA2 | |
| SCHEMBL5032656 | 0.87 | PPARG (0.41) | AKT1CTSLCTSBCTSSATM | |
| SCHEMBL5035679 | 0.87 | NR1D1 (0.52) | NR1D1NR1H3NPC1RAB9ATP53 | |
| SCHEMBL8090953 | 0.85 | ATM (0.39) | NR1D1AKT1OPRD1OPRK1CTSL | |
| SCHEMBL12761956 | 0.85 | NR1D1 (0.34) | NR1D1NR1H3 | |
| SCHEMBL9924674 | 0.83 | NR1D1 (0.33) | NR1D1NR1H3 | |
| SCHEMBL13375696 | 0.81 | NR1D1 (0.33) | NR1D1NR1H3NPC1RAB9A | |
| SCHEMBL23197893 | 0.78 | ACACB (0.31) | NR1D1NR1H3 | |
| SCHEMBL30915258 | 0.78 | AKT1 (0.50) | NR1D1AKT1NR1H3CTSLCTSB | |
| SCHEMBL7570965 | 0.78 | AKT1 (0.50) | NR1D1AKT1NR1H3CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080176339-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2008-07-24 | — | — | US | disclosed |
| US-20080176339-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2008-07-24 | — | — | US | disclosed |
| US-20080176339-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2008-07-24 | — | — | US | disclosed |
| WO-2007082996-A1 | NEUTRAL LABELING REACTANTS AND CONJUGATES DERIVED THEREOF | WALLAC OY (FI) | 2007-07-26 | — | — | WO | disclosed |
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | WALLAC OY (FI) | 2007-07-19 | — | — | US | disclosed |
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | WALLAC OY (FI) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166228-A1 | Neutral labeling reactants and conjugates derived thereof | NAAA, DNPEP, PAM | NR1D1 4118/4885AKT1 3876/4885NR1H3 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.