Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28143011 | 0.85 | CYP2D6 (0.41) | LMNACYP2D6KDM4EKMT2AALDH1A1 | |
| SCHEMBL7982706 | 0.85 | LMNA (0.47) | LMNACYP2D6CYP2C19KDM4EMAPT | |
| SCHEMBL8015502 | 0.80 | LMNA (0.47) | LMNACYP2D6CYP2C19KDM4EMAPT | |
| SCHEMBL15024193 | 0.80 | TP53 (0.40) | LMNAHPGDALDH1A1TP53TDP1 | |
| SCHEMBL19292352 | 0.79 | LMNA (0.48) | LMNACYP2D6CYP2C19KDM4EMAPT | |
| SCHEMBL10348035 | 0.78 | LMNA (0.46) | LMNACYP2D6CYP2C19KDM4EMAPT | |
| SCHEMBL2319965 | 0.77 | LMNA (0.43) | LMNACYP2D6CYP2C19KDM4EMAPT | |
| SCHEMBL28725269 | 0.77 | LMNA (0.45) | LMNACYP2D6CYP2C19KDM4EMAPT | |
| SCHEMBL19711876 | 0.77 | LMNA (0.48) | LMNACYP2D6KDM4EALDH1A1TAAR1 | |
| SCHEMBL19165393 | 0.77 | LMNA (0.48) | LMNACYP2D6KDM4EALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104803861-B | Method for synthesizing tapentadol hydrochloride | 上海博邦医药科技有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-104803861-A | Method for synthesizing tapentadol hydrochloride | SHANGHAI BIOBOND PHARMACEUTICAL CO LTD | 2015-07-29 | — | — | CN | disclosed |
| CN-102202740-B | Perfuming ingredients of the floral and/or anisic type | FIRMENICH & CIE | 2014-03-26 | — | — | CN | disclosed |
| US-8268895-B2 | Perfuming ingredients of the floral and/or anis type | FIRMENICH SA (CH) | 2012-09-18 | — | — | US | disclosed |
| US-8268895-B2 | Perfuming ingredients of the floral and/or anis type | FIRMENICH SA (CH) | 2012-09-18 | — | — | US | disclosed |
| US-8268895-B2 | Perfuming ingredients of the floral and/or anis type | FIRMENICH SA (CH) | 2012-09-18 | — | — | US | disclosed |
| CN-102202740-A | Perfuming ingredients of the floral and/or anisic type | FIRMENICH & CIE | 2011-09-28 | — | — | CN | disclosed |
| US-20110229426-A1 | PERFUMING INGREDIENTS OF THE FLORAL AND/OR ANIS TYPE | FIRMENICH SA (CH) | 2011-09-22 | — | — | US | disclosed |
| US-20110229426-A1 | PERFUMING INGREDIENTS OF THE FLORAL AND/OR ANIS TYPE | FIRMENICH SA (CH) | 2011-09-22 | — | — | US | disclosed |
| US-20110229426-A1 | PERFUMING INGREDIENTS OF THE FLORAL AND/OR ANIS TYPE | FIRMENICH SA (CH) | 2011-09-22 | — | — | US | disclosed |
| EP-2352560-A1 | PERFUMING INGREDIENTS OF THE FLORAL AND/OR ANIS TYPE | Firmenich S.A. (CH) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010052636-A1 | PERFUMING INGREDIENTS OF THE FLORAL AND/OR ANIS TYPE | FIRMENICH SA (CH) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110229426-A1 | PERFUMING INGREDIENTS OF THE FLORAL AND/OR ANIS TYPE | OPRM1, CCR4, RCOR1 | LMNA 4253/4885CYP2D6 377/4885CYP2C19 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.