SCHEMBL7982706

SCHEMBL7982706

C=CC(C)C(C=C)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.47
TAAR1 Q96RJ0 3/20 0.38
KDM4E B2RXH2 2/20 0.37
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
CYP2D6 P10635 1/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 3/20 0.35
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
TRPA1 O75762 1/20 0.35
CYP2C19 P33261 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35
DPP4 P27487 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8015502 0.86 LMNA (0.47) LMNATAAR1KDM4EADRA2AADRA2C
SCHEMBL19292352 0.85 LMNA (0.48) LMNATAAR1KDM4ECYP2D6ALDH1A1
SCHEMBL28553234 0.85 LMNA (0.40) LMNATAAR1KDM4EADRA2AADRA2C
SCHEMBL2319798 0.85 LMNA (0.47) LMNATAAR1KDM4EADRA2AADRA2C
SCHEMBL10348035 0.84 LMNA (0.46) LMNATAAR1KDM4EADRA2AADRA2C
SCHEMBL28725269 0.82 LMNA (0.45) LMNATAAR1KDM4EADRA2AADRA2C
SCHEMBL3804766 0.82 LMNA (0.45) LMNATAAR1KDM4EADRA2AADRA2C
SCHEMBL19165393 0.82 LMNA (0.48) LMNATAAR1KDM4EADRA2AADRA2C
SCHEMBL19711876 0.82 LMNA (0.48) LMNATAAR1KDM4EADRA2AADRA2C
Hydrochloric Acid SCHEMBL9147182 0.80 ALDH1A1 (0.50) LMNATAAR1KDM4EADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1121977-C Thermoplastic resin coated ammonium polyphosphate and process for producing the same BADENHAYM IBERLIKA S A (ES) 2003-09-24 CN disclosed
US-6291068-B1 CORES WITH COATING LAYER, AMMONIUM POLYPHOSPHATE AND THERMOSETTING RESIN, MELAMINE MONOMER OR SURFACE TREATED LAYER CHISSO CORPORATION (JP) 2001-09-18 US disclosed
CN-1229399-A Thermoplastic resin coated ammonium polyphosphate and process for preparation thereof CHISSO CORP (JP) 1999-09-22 CN disclosed
EP-0924166-A1 THERMOPLASTIC-COATED AMMONIUM POLYPHOSPHATE AND PROCESS FOR THE PREPARATION THEREOF CHISSO CORPORATION (JP) 1999-06-23 EP disclosed