SCHEMBL23198637

SCHEMBL23198637

C=Cn1c(=O)oc2cc(Br)cnc21

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.38
PDE4B Q07343 1/20 0.38
PTPN7 P35236 3/20 0.32
DUSP3 P51452 2/20 0.32
GAPDH P04406 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
FGFR1 P11362 1/20 0.30
FGFR4 P22455 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23198644 0.81 HPGD (0.38) HSD17B10MEN1ALDH1A1KMT2AFGFR1
SCHEMBL8918642 0.79 ALDH1A1 (0.36) HSD17B10PDE4BALDH1A1KMT2A
SCHEMBL23198632 0.77 ALDH1A1 (0.34) MEN1ALDH1A1POLBMAPTKMT2A
SCHEMBL7328412 0.76 HSD17B10 (0.53) HSD17B10PDE4BMEN1ALDH1A1POLB
SCHEMBL17418888 0.73 PDE4B (0.43) HSD17B10PDE4BALDH1A1KMT2A
SCHEMBL8627148 0.70 PDE4B (0.36) HSD17B10PDE4BALDH1A1KMT2A
SCHEMBL32686762 0.68 PDE4B (0.38) HSD17B10PDE4BALDH1A1MAPTKMT2A
SCHEMBL8918139 0.68 HSD17B10 (0.38) HSD17B10PDE4BMEN1ALDH1A1KMT2A
SCHEMBL7316292 0.68 NPC1 (0.63) HSD17B10ALDH1A1POLB
SCHEMBL8626898 0.66 TSHR (0.56) HSD17B10MEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3802547-A1 PROCESS FOR PRODUCING COMPOUNDS CONTAINING AN OXAZOLOPYRIDINONE FUNCTIONAL GROUP Biocidal Alternative Solutions (BE) 2021-04-14 EP disclosed