Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 3/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | PRKACG | P22612 | 1/20 | 0.45 |
| ▸ | PRKACB | P22694 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198967 | 0.83 | BCL2 (0.61) | PTPN1ELANEPGAM1LCKPRKACA | |
| SCHEMBL28232665 | 0.83 | PTPN1 (0.60) | PTPN1ELANEPGAM1LCKPRKACA | |
| SCHEMBL436684 | 0.79 | BCL2 (0.64) | PTPN1ELANEPGAM1MAPTMEN1 | |
| SCHEMBL29066488 | 0.78 | ACLY (0.52) | PTPN1ELANEPGAM1LCKPRKACA | |
| SCHEMBL16226807 | 0.77 | ELANE (0.68) | PTPN1ELANEPGAM1LCKPRKACA | |
| SCHEMBL28872301 | 0.76 | PTPN1 (0.55) | PTPN1ELANEPGAM1LCKPRKACA | |
| SCHEMBL2252533 | 0.75 | CA1 (0.57) | PTPN1LCKPRKACAPRKACGPRKACB | |
| SCHEMBL7451901 | 0.75 | CA1 (0.57) | PTPN1LCKPRKACAPRKACGPRKACB | |
| SCHEMBL16226415 | 0.74 | PTPN1 (0.53) | PTPN1ELANEPGAM1LCKPRKACA | |
| SCHEMBL29173163 | 0.73 | ESR1 (0.67) | PTPN1LCKPRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801507-A2 | TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION | ETH Zurich (CH) | 2021-04-14 | — | — | EP | claimed |