Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988851 | 0.86 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL31491403 | 0.84 | KDM4E (0.50) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL17240307 | 0.84 | KDM4E (0.50) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL632171 | 0.84 | GRM5 (0.59) | ALDH1A1L3MBTL1GAAKDM4EHSD17B10 | |
| SCHEMBL7424178 | 0.84 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL27643068 | 0.83 | GRM5 (0.60) | L3MBTL1GRM5NPC1MAPTSMN1; SMN2 | |
| SCHEMBL18261150 | 0.81 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL31250021 | 0.80 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1GAAHTTMAPT | |
| SCHEMBL13156285 | 0.80 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1GAAHTTMAPT | |
| SCHEMBL20141519 | 0.80 | CA12 (0.46) | ALDH1A1L3MBTL1GRM5DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801494-A1 | ANTIBACTERIAL AGENTS: DUAL-TARGETED RNA POLYMERASE INHIBITORS | Rutgers, The State University of New Jersey (US) | 2021-04-14 | — | — | EP | disclosed |