Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200464 | 0.84 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL5988851 | 0.82 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL5761335 | 0.81 | ADRA2C (0.51) | ALDH1A1GAAKDM4EHSD17B10NPC1 | |
| SCHEMBL13156285 | 0.80 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1GAAHTTSMN1; SMN2 | |
| SCHEMBL31250021 | 0.80 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1GAAHTTSMN1; SMN2 | |
| SCHEMBL7434718 | 0.79 | MAPT (0.65) | ALDH1A1L3MBTL1HTTTDP1RAB9A | |
| SCHEMBL18261150 | 0.78 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL21332689 | 0.76 | MAPT (0.55) | ALDH1A1GAAHTTKDM4EHSD17B10 | |
| SCHEMBL29937765 | 0.74 | ALDH1A1 (0.93) | ALDH1A1L3MBTL1GAAHTTKDM4E | |
| SCHEMBL1136241 | 0.74 | ALDH1A1 (0.93) | ALDH1A1L3MBTL1GAAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117651-A1 | NEW BIS-BENZIMIDAZOLES | Bayer Aktiengesellschaft (DE) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020401-A1 | NEW BIS-BENZIMIDAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-04-13 | — | — | WO | disclosed |