Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129649 | 0.83 | SMARCA2 (0.47) | CA12CA1CA2CA9CA7 | |
| SCHEMBL23200464 | 0.80 | ALDH1A1 (0.62) | DPP4DPP9GRM5MAPTALDH1A1 | |
| SCHEMBL632171 | 0.79 | GRM5 (0.59) | DPP4DPP9GRM5MAPTALDH1A1 | |
| SCHEMBL20129648 | 0.78 | KDR (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL27643068 | 0.78 | GRM5 (0.60) | GRM5MAPTL3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL27200524 | 0.78 | SLC6A9 (0.54) | CA12CA1CA2CA9CA7 | |
| Hydrochloric Acid SCHEMBL20141168 | 0.77 | KDR (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL13490136 | 0.74 | HSD11B1 (0.52) | GRM5 | |
| SCHEMBL3708569 | 0.74 | SCD5 (0.58) | GRM5MAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL20140841 | 0.72 | CYP1A2 (0.52) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538091-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089499-A1 | PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |