Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684043 | 0.86 | CASP6 (0.49) | CA2CYP1A2CYP3A4LMNAKDM4E | |
| SCHEMBL2253267 | 0.83 | TSHR (0.53) | CA2CYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL5184754 | 0.83 | GPR35 (0.51) | CA2CYP1A2CYP3A4LMNASNCA | |
| SCHEMBL10615900 | 0.83 | BACE1 (0.49) | CA2CYP1A2SNCAALDH1A1CASP6 | |
| SCHEMBL23200508 | 0.82 | ATM (0.51) | CYP1A2NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29902892 | 0.82 | ATM (0.51) | CA2LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL28847424 | 0.82 | ATM (0.51) | CA2LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL25407643 | 0.82 | MEN1 (0.46) | CYP1A2RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL30599924 | 0.82 | MEN1 (0.46) | CYP1A2RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL30764869 | 0.82 | TSHR (0.53) | CA2CYP3A4NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090216046-A1 | SELECTIVE ACYLATION OF 4-SUBSTITUTED-1,3-PHENYLENEDIAMINE | WYETH (US) | 2009-08-27 | — | — | US | disclosed |
| EP-1943212-A2 | SELECTIVE ACYLATION OF 4-SUBSTITUTED-1,3-PHENYLENEDIAMINE | Wyeth a Corporation of the State of Delaware (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007086956-A2 | SELECTIVE ACYLATION OF 4-SUBSTITUTED-1,3-PHENYLENEDIAMINE | WYETH (US) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090216046-A1 | SELECTIVE ACYLATION OF 4-SUBSTITUTED-1,3-PHENYLENEDIAMINE | AOC3, CBR3, C9 | CA2 609/4885CYP1A2 236/4885CYP3A4 210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.