Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201233 | 1.00 | PPARG (0.47) | PPARGPPARDPPARALMNAGAA | |
| SCHEMBL31153320 | 1.00 | PPARG (0.47) | PPARGPPARDPPARALMNAGAA | |
| SCHEMBL23201254 | 1.00 | PPARG (0.47) | PPARGPPARDPPARALMNAGAA | |
| SCHEMBL22420293 | 0.85 | CNR2 (0.54) | PPARGPPARDPPARALMNAGAA | |
| SCHEMBL6656697 | 0.84 | PPARG (0.61) | PPARGPPARDPPARALMNAGAA | |
| SCHEMBL477320 | 0.83 | CNR2 (0.58) | PPARGPPARDPPARALMNAGAA | |
| SCHEMBL424542 | 0.83 | CNR2 (0.48) | SMN1; SMN2CNR2ERN1KMT2AFYN | |
| SCHEMBL16541896 | 0.78 | PDE4A (0.57) | HTTSMN1; SMN2ACHEL3MBTL1TDP1 | |
| SCHEMBL12113567 | 0.78 | CNR2 (0.54) | SMN1; SMN2CNR2KMT2AFYN | |
| SCHEMBL16931596 | 0.76 | CYP17A1 (0.56) | PPARGPPARDPPARASMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3805193-B1 | NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF | UNIV EWHA IND COLLABORATION (KR) | 2024-09-11 | — | — | EP | disclosed |
| US-12043594-B2 | Biphenyl derivative compound and use thereof | EWHA University—Industry Collaboration Foundation (KR) | 2024-07-23 | — | — | US | disclosed |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2021-07-08 | — | — | US | disclosed |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2021-07-08 | — | — | US | disclosed |
| EP-3805193-A1 | NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF | Ewha University-Industry Collaboration Foundation (KR) | 2021-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043594-B2 | Biphenyl derivative compound and use thereof | NME4, PCK2, DNAJA3 | PPARG 1274/4885PPARD 941/4885PPARA 1508/4885 |
| US-20210206706-A1 | Novel Biphenyl Derivative Compound and Use Thereof | NME4, PCK2, DNAJA3 | PPARG 1803/4885PPARD 1402/4885PPARA 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.