SCHEMBL6656697

SCHEMBL6656697

COc1ccc(C(O)c2ccc(OC)c(OC)c2)cc1OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.61
PPARD Q03181 1/20 0.61
PPARA Q07869 1/20 0.61
ACHE P22303 4/20 0.57
KMT2A Q03164 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
LMNA P02545 1/20 0.53
GAA P10253 1/20 0.53
HTT P42858 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TUBB4A P04350 2/20 0.49
TUBB P07437 2/20 0.49
TUBA3C P0DPH7 2/20 0.49
TUBA1B P68363 2/20 0.49
TUBA4A P68366 2/20 0.49
TUBB4B P68371 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL477320 0.90 CNR2 (0.58) PPARGPPARDPPARAACHEKMT2A
SCHEMBL16231317 0.90 PPARG (0.53) PPARGPPARDPPARAACHEKMT2A
SCHEMBL25688701 0.90 PPARG (0.57) PPARGPPARDPPARAACHEKMT2A
SCHEMBL24050778 0.89 PPARG (0.51) PPARGPPARDPPARAACHEKMT2A
SCHEMBL16231311 0.86 PPARG (0.57) PPARGPPARDPPARAACHEKMT2A
SCHEMBL22420326 0.86 LMNA (0.53) PPARGPPARDPPARAACHEKMT2A
SCHEMBL25688708 0.86 ALOX5 (0.57) PPARGPPARDPPARAACHEKMT2A
SCHEMBL22420293 0.86 CNR2 (0.54) PPARGPPARDPPARAACHEKMT2A
SCHEMBL4818551 0.85 PPARG (0.51) PPARGPPARDPPARAACHEL3MBTL1
SCHEMBL670305 0.84 PPARG (0.59) PPARGPPARDPPARAACHEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-08-05 US disclosed
US-20240294514-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF APOGEE PHARMACEUTICALS, INC. (CA) 2024-09-05 US disclosed
EP-3109703-B1 PHOTOSENSITIZATION CHEMICAL-AMPLIFICATION TYPE RESIST MATERIAL, AND METHOD FOR FORMING PATTERN USING SAME TOKYO ELECTRON LTD (JP) 2020-12-30 EP disclosed
US-10772858-B2 Benzhydrol derivatives for the management of conditions related to hypoxia inducible factors GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2020-09-15 US disclosed
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting TOKYO ELECTRON LIMITED (JP) 2018-07-17 US disclosed
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting TOKYO ELECTRON LIMITED (JP) 2018-07-17 US disclosed
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method JSR CORPORATION (JP) 2018-07-10 US disclosed
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method JSR CORPORATION (JP) 2018-07-10 US disclosed
US-9971247-B2 Pattern-forming method OSAKA UNIVERSITY (JP) 2018-05-15 US disclosed
US-9971247-B2 Pattern-forming method OSAKA UNIVERSITY (JP) 2018-05-15 US disclosed
US-20170052449-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL, PATTERN-FORMING METHOD, COMPOUND, AND PRODUCTION METHOD OF COMPOUND OSAKA UNIVERSITY (JP) 2017-02-23 US disclosed
US-20170052450-A1 PATTERN-FORMING METHOD OSAKA UNIVERSITY (JP) 2017-02-23 US disclosed
US-20170052450-A1 PATTERN-FORMING METHOD OSAKA UNIVERSITY (JP) 2017-02-23 US disclosed
US-20160357103-A1 PHOTOSENSITIZATION CHEMICAL-AMPLIFICATION TYPE RESIST MATERIAL, METHOD FOR FORMING PATTERN USING SAME, SEMICONDUCTOR DEVICE, MASK FOR LITHOGRAPHY, AND TEMPLATE FOR NANOIMPRINTING TOKYO ELECTRON LIMITED (JP) 2016-12-08 US disclosed
US-20160357103-A1 PHOTOSENSITIZATION CHEMICAL-AMPLIFICATION TYPE RESIST MATERIAL, METHOD FOR FORMING PATTERN USING SAME, SEMICONDUCTOR DEVICE, MASK FOR LITHOGRAPHY, AND TEMPLATE FOR NANOIMPRINTING TOKYO ELECTRON LIMITED (JP) 2016-12-08 US disclosed
EP-1291375-B1 Functional groups for thermal crosslinking of polymeric systems AIR PROD & CHEM (US) 2004-06-30 EP disclosed
EP-0939096-B1 Functional groups for thermal crosslinking of polymeric systems AIR PROD & CHEM (US) 2003-11-26 EP disclosed
EP-1291375-A1 Functional groups for thermal crosslinking of polymeric systems AIR PRODUCTS AND CHEMICALS, INC. (US) 2003-03-12 EP disclosed
US-6060170-A A POLYARYLENE ETHER MODIFIED BY ALKOXYARYLENE KETONE GROUPS CROSSLINKED TO FORM A HEAT RESISTANT, LOW DIELECTRIC, ELASTIC MODULUS ABOVE THE INCREASED GLASS TRANSITION TEMPERATURE; VERY FINE DIMENSIONED INTEGRATED CIRCUITS; REPLACES SILICA AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-05-09 US disclosed
EP-0939096-A2 Functional groups for thermal crosslinking of polymeric systems AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10025187-B2 Photosensitization chemical-amplification type resist material, method for forming pattern using same, semiconductor device, mask for lithography, and template for nanoimprinting ASIC1, ASIC3, CLTA PPARG 2621/4885PPARD 3705/4885PPARA 676/4885
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof MGLL, PNLIP, LPL PPARG 552/4885PPARD 737/4885PPARA 1339/4885
US-20240294514-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF MGLL, PNLIP, LPL PPARG 552/4885PPARD 737/4885PPARA 1339/4885
US-10018911-B2 Chemically amplified resist material and resist pattern-forming method SLC11A2, XRCC5, RAD54L PPARG 4454/4885PPARD 4862/4885PPARA 3604/4885
US-20170052449-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL, PATTERN-FORMING METHOD, COMPOUND, AND PRODUCTION METHOD OF COMPOUND RER1, POLR1A, FEM1B PPARG 3955/4885PPARD 4680/4885PPARA 2473/4885
US-10772858-B2 Benzhydrol derivatives for the management of conditions related to hypoxia inducible factors HIF1A, HIF1AN, EGLN2 PPARG 148/4885PPARD 555/4885PPARA 540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.