Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354428 | 0.87 | PTGS2 (0.61) | PTGS2PTGS1NR3C1PGRNR3C2 | |
| SCHEMBL2351999 | 0.85 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL2351267 | 0.85 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL2348407 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1PGR | |
| SCHEMBL2349594 | 0.80 | PTGS2 (0.58) | PTGS2PTGS1NR3C1PGRNR3C2 | |
| SCHEMBL3337047 | 0.80 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL2349582 | 0.77 | PTGS2 (0.49) | PTGS2PTGS1PGR | |
| SCHEMBL1961471 | 0.77 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL2032931 | 0.75 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL10015964 | 0.74 | PTGS2 (0.56) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658644-B2 | Pyridazine derivatives, processes for their preparation and their use as fungicides | SYNGENTA CROP PROTECTION, LLC (US) | 2014-02-25 | — | — | US | disclosed |
| EP-2531491-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | Syngenta Participations AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| US-20120295876-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2011095461-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295876-A1 | PYRIDAZINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | CYP4Z1, CYP4F3, CYP4F2 | PTGS2 3699/4885PTGS1 3709/4885NR3C1 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.