SCHEMBL10015964

SCHEMBL10015964

CC1(O)OC(=O)C(c2c(F)cccc2F)=C1c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 17/20 0.56
PTGS1 P23219 5/20 0.47
HCAR2 Q8TDS4 2/20 0.38
HCAR3 P49019 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4583693 0.87 PTGS2 (0.47) PTGS2PTGS1CA1CA2CA7
SCHEMBL2350613 0.87 PTGS2 (0.60) PTGS2PTGS1
SCHEMBL15974714 0.81 PTGS2 (0.45) PTGS2PTGS1CA1CA2CA7
SCHEMBL19446292 0.80 PTGS2 (0.55) PTGS2PTGS1
SCHEMBL2354428 0.80 PTGS2 (0.61) PTGS2PTGS1
SCHEMBL17472949 0.80 PTGS2 (0.52) PTGS2PTGS1HCAR2HCAR3
SCHEMBL2351999 0.78 PTGS2 (0.56) PTGS2PTGS1
SCHEMBL4583216 0.78 PTGS2 (0.52) PTGS2PTGS1HCAR2HCAR3CA1
SCHEMBL3974343 0.78 PTGS2 (0.58) PTGS2PTGS1
SCHEMBL2349582 0.78 PTGS2 (0.49) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200385328-A1 METHOD FOR PRODUCING BENZOYL FORMIC ACID COMPOUND AND PYRIDAZINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-12-10 US disclosed
CN-111225898-A Process for producing benzoylcarboxylic acid compound and pyridazine compound 住友化学株式会社 2020-06-02 CN disclosed
EP-2958899-B1 PROCESS FOR PRODUCING PYRIDAZINONE COMPOUND AND PRODUCTION INTERMEDIATES THEREOF SUMITOMO CHEMICAL CO (JP) 2017-10-11 EP disclosed
EP-2958899-B1 PROCESS FOR PRODUCING PYRIDAZINONE COMPOUND AND PRODUCTION INTERMEDIATES THEREOF SUMITOMO CHEMICAL CO (JP) 2017-10-11 EP disclosed
US-9650347-B2 Process for producing pyridazinone compound and production intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-16 US disclosed
US-9650347-B2 Process for producing pyridazinone compound and production intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-16 US disclosed
US-9650347-B2 Process for producing pyridazinone compound and production intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-16 US disclosed
US-20150376138-A1 PROCESS FOR PRODUCING PYRIDAZINONE COMPOUND AND PRODUCTION INTERMEDIATES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-31 US disclosed
US-20150376138-A1 PROCESS FOR PRODUCING PYRIDAZINONE COMPOUND AND PRODUCTION INTERMEDIATES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-31 US disclosed
US-20150376138-A1 PROCESS FOR PRODUCING PYRIDAZINONE COMPOUND AND PRODUCTION INTERMEDIATES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-31 US disclosed
US-20130137683-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130137683-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130137658-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130137658-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130137692-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130137658-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-30 US disclosed
US-20130131067-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131067-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
US-20130131067-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-23 US disclosed
WO-2012020772-A1 PLANT DISEASE CONTROL COMPOSITION AND APPLICATION FOR SAME 住友化学株式会社 (JP) 2012-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376138-A1 PROCESS FOR PRODUCING PYRIDAZINONE COMPOUND AND PRODUCTION INTERMEDIATES THEREOF NQO1, XDH, PDXK PTGS2 1045/4885PTGS1 687/4885HCAR2 567/4885
US-20130137658-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF ERG28, CYP4F3, TH PTGS2 1961/4885PTGS1 2614/4885HCAR2 3692/4885
US-20130131067-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF BROX, BOLA2; BOLA2B, GBA2 PTGS2 3007/4885PTGS1 3736/4885HCAR2 775/4885
US-20200385328-A1 METHOD FOR PRODUCING BENZOYL FORMIC ACID COMPOUND AND PYRIDAZINE COMPOUND SDHA, FDPS, NDUFS5 PTGS2 325/4885PTGS1 797/4885HCAR2 537/4885
US-20130137683-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF PNPO, PAOX, PIR PTGS2 3520/4885PTGS1 3971/4885HCAR2 2041/4885
US-20130137692-A1 PLANT DISEASE CONTROLLING COMPOSITION AND USE THEREOF BROX, CHRM2, BRD1 PTGS2 868/4885PTGS1 1079/4885HCAR2 573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.