Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201606 | 0.86 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNANPC1TSHR | |
| SCHEMBL31188610 | 0.86 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1LMNANPC1TSHR | |
| SCHEMBL4724490 | 0.86 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1LMNANPC1TSHR | |
| SCHEMBL23041012 | 0.78 | MAPT (0.53) | L3MBTL1ALDH1A1LMNAHPGDKDM4E | |
| Nitric Acid SCHEMBL28953171 | 0.78 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1LMNANPC1TSHR | |
| Hydrochloric Acid SCHEMBL1076729 | 0.78 | LMNA (0.42) | L3MBTL1ALDH1A1LMNAKDM4EMAPK1 | |
| SCHEMBL11546391 | 0.77 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1LMNANPC1TSHR | |
| SCHEMBL28531811 | 0.76 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1LMNANPC1TSHR | |
| SCHEMBL3729269 | 0.75 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1LMNANPC1TSHR | |
| SCHEMBL29786652 | 0.75 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1LMNANPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | claimed |