Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21700700 | 0.99 | BACE1 (0.50) | BACE1KDM4EMEN1KMT2AHTR6 | |
| SCHEMBL16279248 | 0.95 | BACE1 (0.47) | BACE1KDM4EMEN1KMT2AHTR6 | |
| SCHEMBL30918477 | 0.89 | KDM4E (0.47) | BACE1KDM4EMEN1KMT2AHTR6 | |
| SCHEMBL24983954 | 0.89 | KDM4E (0.47) | BACE1KDM4EMEN1KMT2AHTR6 | |
| SCHEMBL17893724 | 0.84 | ALDH1A1 (0.45) | KDM4EMEN1KMT2ANR4A2ALDH1A1 | |
| SCHEMBL17916000 | 0.84 | OPRK1 (0.50) | KDM4EMEN1KMT2ANR4A2ALDH1A1 | |
| SCHEMBL652911 | 0.83 | HTR3E (0.56) | KDM4EMEN1KMT2AHTR6HTR7 | |
| SCHEMBL19680543 | 0.83 | MAPT (0.56) | BACE1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL10267394 | 0.82 | ALDH1A1 (0.49) | KDM4EMEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL29249371 | 0.82 | KDM4E (0.44) | BACE1KDM4EMEN1KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802500-A1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |