SCHEMBL23201795

SCHEMBL23201795

COC(=O)C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
GAA P10253 3/20 0.51
HSD11B1 P28845 1/20 0.48
MAPT P10636 3/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
POLB P06746 4/20 0.47
KMT2A Q03164 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
AADAT Q8N5Z0 1/20 0.41
MEN1 O00255 1/20 0.41
TACR1 P25103 1/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
GLA P06280 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23201794 1.00 ALDH1A1 (0.51) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL23201840 0.89 MAPT (0.58) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL21501021 0.89 MAPT (0.58) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL19597541 0.82 ALDH1A1 (0.70) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL19597540 0.82 ALDH1A1 (0.70) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL21501014 0.80 ALDH1A1 (0.56) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL21501052 0.80 HSD11B1 (0.67) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL21501078 0.78 HSD11B1 (0.59) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL21501019 0.78 ALDH1A1 (0.56) ALDH1A1GAAHSD11B1MAPTNPC1
SCHEMBL21501050 0.78 ALDH1A1 (0.56) ALDH1A1GAAHSD11B1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805237-B1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND JIANGSU CHUANGTE PHARMACEUTICAL TECH CO LTD (CN) 2026-01-28 EP disclosed
EP-3805237-A1 SYNTHESIS AND USES OF PEPTIDE BORATE ESTER COMPOUND Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. (CN) 2021-04-14 EP disclosed