Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | ESRRA | P11474 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901452 | 0.79 | RORC (0.34) | RORCRHEB | |
| SCHEMBL2321596 | 0.77 | MCL1 (0.40) | RORCESRRA | |
| SCHEMBL2319768 | 0.72 | L3MBTL1 (0.35) | RORCESRRAMAPT | |
| SCHEMBL23607234 | 0.70 | CSNK2A2 (0.36) | MAPT | |
| SCHEMBL30698370 | 0.69 | MAPT (0.45) | TP53MAPTRHEB | |
| SCHEMBL4777935 | 0.69 | MAPT (0.45) | TP53MAPTRHEB | |
| SCHEMBL15780474 | 0.69 | MAPT (0.37) | TP53MAPTRHEB | |
| SCHEMBL30885833 | 0.66 | PDE10A (0.34) | RHEB | |
| SCHEMBL24402025 | 0.66 | RHEB (0.39) | RHEB | |
| SCHEMBL31569633 | 0.66 | MAPT (0.49) | TP53MAPTRHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097491-A1 | BENZIMIDAZOLE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-08-11 | — | — | WO | disclosed |