SCHEMBL2320474

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL13834975	0.99	MAP4K1 (0.52)	MAP4K1ALKMETPAK1PIM1
	SCHEMBL2324841	0.92	MAP4K3 (0.47)	MAP4K1ALKMETPAK1PIM1
	SCHEMBL2321067	0.92	INPPL1 (0.50)	MAP4K1ALKMETPAK1PIM1
	Hydrochloric Acid SCHEMBL2324061	0.91	INPPL1 (0.49)	MAP4K1ALKMETPAK1PIM1
	SCHEMBL2323319	0.89	MET (0.43)	MAP4K1METEGFRJAK2JAK1
	SCHEMBL12527177	0.89	MAP4K1 (0.58)	MAP4K1ALKMETPAK1PIM1
	SCHEMBL2324969	0.89	MET (0.44)	MAP4K1ALKMETPIM1MAP4K3
	Hydrochloric Acid SCHEMBL2325279	0.88	MET (0.43)	MAP4K1ALKMETPIM1MAP4K3
	SCHEMBL12440741	0.88	PIM1 (0.42)	MAP4K1ALKMETPIM1MAP4K3
	SCHEMBL2365416	0.86	MAP4K1 (0.40)	MAP4K1METPIM1EGFRJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.