Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11515624 | 0.98 | HTT (0.58) | HTTSMN1; SMN2CTBP2ALDH1A1CYP3A4 | |
| SCHEMBL18827708 | 0.83 | HTT (0.58) | HTTSMN1; SMN2CTBP2ALDH1A1CYP3A4 | |
| SCHEMBL3152379 | 0.83 | HTT (0.58) | HTTSMN1; SMN2CTBP2ALDH1A1CYP3A4 | |
| SCHEMBL11879153 | 0.81 | HTT (0.56) | HTTSMN1; SMN2CTBP2ALDH1A1CYP3A4 | |
| SCHEMBL9064975 | 0.81 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL4924884 | 0.81 | F2RL1 (0.64) | SMN1; SMN2ALDH1A1POLBNPC1F2RL1 | |
| SCHEMBL8306612 | 0.81 | LMNA (0.50) | SMN1; SMN2ALDH1A1CYP3A4TP53KDM4E | |
| SCHEMBL11876987 | 0.80 | HTT (0.54) | HTTSMN1; SMN2CTBP2ALDH1A1CYP3A4 | |
| SCHEMBL3628705 | 0.79 | HTT (0.68) | HTTSMN1; SMN2CTBP2ALDH1A1CYP3A4 | |
| SCHEMBL9817167 | 0.79 | HTT (0.53) | HTTSMN1; SMN2CTBP2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966214-B1 | SYNTHESIS OF COELENTERAZINE | INT PAPER CO (US) | 2023-12-13 | — | — | EP | disclosed |
| EP-2568953-A2 | TRIAZINES AS REACTION ACCELERATORS | Merck Patent GmbH (DE) | 2013-03-20 | — | — | EP | disclosed |
| WO-2011141111-A2 | TRIAZINES AS REACTION ACCELERATORS | MERCK PATENT GMBH (DE) | 2011-11-17 | — | — | WO | disclosed |
| EP-2352725-A1 | QUINOXALINE-BASED LXR MODULATORS | Wyeth LLC (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010054229-A1 | QUINOXALINE-BASED LXR MODULATORS | WYETH LLC (US) | 2010-05-14 | — | — | WO | disclosed |
| EP-0914318-A1 | PYRAZINES | KINGS COLLEGE LONDON (GB) | 1999-05-12 | — | — | EP | disclosed |
| WO-1997043267-A1 | PYRAZINES | KINGS COLLEGE LONDON (GB) | 1997-11-20 | — | — | WO | disclosed |
| US-4161476-A | α-Halo-2-oxo-1-azetidinemethane-carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4052408-A | OXYACETIC ACID COMPOUNDS AND PROCESS FOR THEIR MANUFACTURE | CIBA-GEIGY CORPORATION (US) | 1977-10-04 | — | — | US | disclosed |