SCHEMBL2320683

SCHEMBL2320683

O=C(O)[C@@H](NO)C(O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
MAPK1 P28482 1/20 0.50
CA1 P00915 3/20 0.49
CA2 P00918 3/20 0.49
CYP2D6 P10635 2/20 0.46
SRC P12931 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
CHRM2 P08172 1/20 0.44
ADRA1A P35348 1/20 0.44
AOC3 Q16853 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2466763 1.00 LMNA (0.50) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL7431162 0.82 ADRA2C (0.57) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL7431159 0.82 ADRA2C (0.57) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL15984955 0.82 LMNA (0.48) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL28717180 0.80 LMNA (0.47) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL28717182 0.80 LMNA (0.47) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL19625534 0.79 CA1 (0.52) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL13957303 0.79 ADRA2C (0.48) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL10346709 0.79 CA1 (0.52) LMNAMAPK1CA1CA2CYP2D6
SCHEMBL10346708 0.79 CA1 (0.52) LMNAMAPK1CA1CA2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3559312-B1 REACTION PRODUCTS OF CATECHOL COMPOUNDS AND FUNCTIONALIZED CO-REACTANT COMPOUNDS FOR METAL PRETREATMENT APPLICATIONS HENKEL AG & CO KGAA (DE) 2024-04-24 EP claimed
US-10844421-B2 Composition from lobster hemocyte extracts for detection of lipopolysaccharides, peptidoglycans and 1,3-beta-D-glucans CENTRO DE INVESTIGACION Y DESARROLLO DE MEDICAMENTOS (CIDEM) (CU) 2020-11-24 US claimed
EP-3559312-A1 REACTION PRODUCTS OF CATECHOL COMPOUNDS AND FUNCTIONALIZED CO-REACTANT COMPOUNDS FOR METAL PRETREATMENT APPLICATIONS Henkel AG & Co. KGaA (DE) 2019-10-30 EP claimed
US-20190301023-A1 REACTION PRODUCTS OF CATECHOL COMPOUNDS AND FUNCTIONALIZED CO-REACTANT COMPOUNDS FOR METAL PRETREATMENT APPLICATIONS HENKEL AG & CO. KGAA (DE) 2019-10-03 US claimed
US-20180340206-A1 COMPOSITION FROM LOBSTER HEMOCYTE EXTRACTS FOR DETECTION OF LIPOPOLYSACCHARIDES, PEPTIDOGLYCANS AND 1,3-BETA-D-GLUCANS CENTRO DE INVESTIG Y DESARROLLO DE MEDICAMENTOS CIDEM (CU) 2018-11-29 US claimed
CN-107880294-A Sulfonated poly aryl ether ketone sulfone containing amino/amino-acid functional inorganic particulate compoiste proton exchange film 长春工业大学 2018-04-06 CN claimed
CN-1929829-B (S) -2-N-propylamino-5-hydroxytetraline as D3 agonist SANOL ARZNEI SCHWARZ GMBH 2010-12-15 CN claimed
CN-101532046-A Site-specific incorporation of redox active amino acids into proteins SCRIPPS RESEARCH INST 2009-09-16 CN claimed
JP-9149784-A None JP disclosed
US-12458705-B2 Antibody-oligonucleotide conjugates ANGIEX, INC. (US) 2025-11-04 US disclosed
US-12428477-B2 Antibody-drug conjugates comprising anti-TM4SF1 antibodies and methods of using the same ANGIEX, INC. (US) 2025-09-30 US disclosed
US-12377294-B2 Anti-CD3 antibody folate bioconjugates and their uses AMBRX, INC. (US) 2025-08-05 US disclosed
EP-4559928-A2 CHIMERIC ANTIGEN RECEPTOR EFFECTOR CELL SWITCHES WITH HUMANIZED TARGETING MOIETIES AND/OR OPTIMIZED CHIMERIC ANTIGEN RECEPTOR INTERACTING DOMAINS AND USES THEREOF The Scripps Research Institute (US) 2025-05-28 EP disclosed
US-20250152730-A1 ANTI-TM4SF1 ANTIBODY-DRUG CONJUGATES COMPRISING CLEAVABLE LINKERS AND METHODS OF USING SAME ANGIEX, INC. 2025-05-15 US disclosed
WO-1999036393-A1 INHIBITORS OF α4 MEDIATED CELL ADHESION TANABE SEIYAKU CO., LTD. (JP) 1999-07-22 WO disclosed
CN-1192746-A Peptide derivatives and angiotensin IV receptor agonists SAGAMI CHEM RES (JP) 1998-09-09 CN disclosed
JP-H09149784-A SENSOR FOR DETERMINING PROTEASE ACTIVITY NEW JAPAN RADIO CO LTD 1997-06-10 JP disclosed
EP-0136996-B1 STABILIZATION OF L-PHENYLALANINE AMMONIA-LYASE ENZYME Monsanto Company (US) 1990-04-11 EP disclosed
US-4562151-A SYNTHESIZING PHENYLALANINES FROM CINNAMIC OR ACRYLIC ACID DERIVATIVES USING A POLYHYDRIC ALCOHOL OR ETHYLENE OXIDE ADDUCT PROMOTER MONSANTO COMPANY (US) 1985-12-31 US disclosed
EP-0136996-A2 Stabilization of L-phenylalanine ammonia-lyase enzyme Monsanto Company (US) 1985-04-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428477-B2 Antibody-drug conjugates comprising anti-TM4SF1 antibodies and methods of using the same TM9SF4, TM9SF2, TM9SF3 LMNA 2873/4885MAPK1 4662/4885CA1 3036/4885
US-12377294-B2 Anti-CD3 antibody folate bioconjugates and their uses FOLR2, FOLR1, CD2 LMNA 4576/4885MAPK1 4628/4885CA1 2904/4885
US-12458705-B2 Antibody-oligonucleotide conjugates TM9SF4, TMSB4X, IGSF11 LMNA 2745/4885MAPK1 4629/4885CA1 2747/4885
US-20250152730-A1 ANTI-TM4SF1 ANTIBODY-DRUG CONJUGATES COMPRISING CLEAVABLE LINKERS AND METHODS OF USING SAME TM9SF4, TM9SF2, TMPRSS4 LMNA 2171/4885MAPK1 4409/4885CA1 1735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.