Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | FABP1 | P07148 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949383 | 0.84 | MAPT (0.55) | HSD17B10KDM4EHPGDALDH1A1MEN1 | |
| SCHEMBL30464743 | 0.84 | HSD17B10 (0.71) | HSD17B10KDM4EHPGDTSHRBACE1 | |
| SCHEMBL4571036 | 0.84 | HSD17B10 (0.71) | HSD17B10KDM4EHPGDTSHRBACE1 | |
| SCHEMBL8557281 | 0.79 | L3MBTL1 (0.53) | HSD17B10KDM4EHPGDTSHRIDO1 | |
| SCHEMBL692954 | 0.77 | HSD17B10 (0.45) | HSD17B10KDM4EHPGDTSHRBACE1 | |
| SCHEMBL4571038 | 0.77 | HSD17B10 (0.63) | HSD17B10KDM4EHPGDTSHRBACE1 | |
| SCHEMBL6541555 | 0.76 | IDO1 (0.69) | HSD17B10KDM4EHPGDTSHRBACE1 | |
| SCHEMBL31006473 | 0.76 | IDO1 (0.69) | HSD17B10KDM4EHPGDTSHRBACE1 | |
| SCHEMBL22116870 | 0.75 | KDM4E (0.49) | KDM4EMAPTL3MBTL1 | |
| SCHEMBL8239030 | 0.74 | HSD17B10 (0.59) | HSD17B10KDM4EHPGDTSHRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105775-A | Preparation method of substituted iodobenzene with terminal double bond | 武汉工程大学 | 2022-03-01 | — | — | CN | claimed |
| CN-117229228-A | Synthesis method of 2-thiobenzothiazole compound | 中国人民解放军军事科学院防化研究院 | 2023-12-15 | — | — | CN | disclosed |
| CN-114105775-A | Preparation method of substituted iodobenzene with terminal double bond | 武汉工程大学 | 2022-03-01 | — | — | CN | disclosed |
| US-10167292-B2 | Benzodiazepines as bromodomain inhibitors | Catalyst Therapeutics Pty Ltd. (AU) | 2019-01-01 | — | — | US | disclosed |
| US-10167292-B2 | Benzodiazepines as bromodomain inhibitors | Catalyst Therapeutics Pty Ltd. (AU) | 2019-01-01 | — | — | US | disclosed |
| US-20180273840-A1 | SPIRALLY CONFIGURED CIS-STILBENE/FLUORENE HYBRID MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | CLIPHOR TECHNOLOGY CO., LTD. (TW) | 2018-09-27 | — | — | US | disclosed |
| CN-108463462-A | Benzene phenodiazine * classes are as bromine structural domain inhibitor | 催化剂治疗私人有限公司 | 2018-08-28 | — | — | CN | disclosed |
| EP-3331887-A1 | BENZODIAZEPINES AS BROMODOMAIN INHIBITORS | Catalyst Therapeutics Pty Ltd. (AU) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017020086-A1 | BENZODIAZEPINES AS BROMODOMAIN INHIBITORS | CATALYST THERAPEUTICS PTY LTD (AU) | 2017-02-09 | — | — | WO | disclosed |
| WO-2017020086-A1 | BENZODIAZEPINES AS BROMODOMAIN INHIBITORS | CATALYST THERAPEUTICS PTY LTD (AU) | 2017-02-09 | — | — | WO | disclosed |
| US-8791301-B2 | Method of preparing secondary amine compound using microflow reactor | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNGHEE UNIVERSITY (KR) | 2014-07-29 | — | — | US | disclosed |
| US-20130137900-A1 | NOVEL METHOD OF PREPARING SECONDARY AMINE COMPOUND USING MICROFLOW REACTOR | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNGHEE UNIVERSITY (KR) | 2013-05-30 | — | — | US | disclosed |
| WO-2011096729-A2 | NOVEL METHOD OF PREPARING SECONDARY AMINE COMPOUND USING MICROFLOW REACTOR | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNGHEE UNIVERSITY (KR) | 2011-08-11 | — | — | WO | disclosed |
| US-4360511-A | Amines useful as brain imaging agents | MEDI-PHYSICS, INC. (US) | 1982-11-23 | — | — | US | disclosed |
| EP-0011858-A1 | Radioiodine containing amines, their preparation and their use as brain imaging agents | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137900-A1 | NOVEL METHOD OF PREPARING SECONDARY AMINE COMPOUND USING MICROFLOW REACTOR | SRM, MAOB, HNMT | HSD17B10 2147/4885KDM4E 1707/4885HPGD 2037/4885 |
| US-10167292-B2 | Benzodiazepines as bromodomain inhibitors | BRD1, BRD3, BRD2 | HSD17B10 759/4885KDM4E 1294/4885HPGD 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.