Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681227 | 0.79 | TDP1 (0.33) | LMNAELANEALDH1A1NPSR1USP2 | |
| SCHEMBL2066449 | 0.78 | ADRB1 (0.38) | LMNAPOLBALDH1A1HSD17B10KDM4E | |
| SCHEMBL1246341 | 0.69 | ALDH1A1 (0.43) | LMNAHTTALDH1A1HSD17B10KDM4E | |
| SCHEMBL1110440 | 0.65 | LMNA (0.35) | LMNAPOLBHTTALDH1A1HSD17B10 | |
| SCHEMBL10582630 | 0.61 | LMNA (0.38) | LMNAPOLBHTTALDH1A1HSD17B10 | |
| SCHEMBL3739181 | 0.60 | LMNA (0.36) | LMNAPOLBHTTALDH1A1HSD17B10 | |
| SCHEMBL9093746 | 0.60 | LMNA (0.71) | LMNAPOLBHTTALDH1A1HSD17B10 | |
| SCHEMBL2815977 | 0.58 | KMT2A (0.55) | LMNAPOLBHTTALDH1A1KDM4E | |
| SCHEMBL28646855 | 0.58 | MAPT (0.52) | LMNAHTTALDH1A1HSD17B10GAA | |
| SCHEMBL28640180 | 0.58 | LMNA (0.61) | LMNAHTTALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |