SCHEMBL23213437

SCHEMBL23213437

O=C(c1nccs1)N1CCOCC1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.49
RBP4 P02753 1/20 0.48
SMO Q99835 1/20 0.47
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HTR2C P28335 2/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PHGDH O43175 1/20 0.42
HTT P42858 1/20 0.41
RIPK1 Q13546 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5130274 0.84 RBP4 (0.51) HPGDRBP4SMOALDH1A1SMN1; SMN2
SCHEMBL970704 0.83 RBP4 (0.50) HPGDRBP4SMOALDH1A1SMN1; SMN2
SCHEMBL17761042 0.81 RBP4 (0.49) HPGDRBP4SMOALDH1A1RAB9A
SCHEMBL16862022 0.81 SMO (0.54) RBP4SMOALDH1A1
SCHEMBL28740942 0.80 RBP4 (0.48) RBP4SMOALDH1A1
SCHEMBL694233 0.80 RBP4 (0.48) HPGDRBP4SMOALDH1A1HTR2C
Ethylene SCHEMBL8381035 0.78 RBP4 (0.46) RBP4SMOALDH1A1
SCHEMBL16862162 0.77 SMO (0.48) RBP4SMOALDH1A1
SCHEMBL698614 0.76 RBP4 (0.57) RBP4SMOALDH1A1
SCHEMBL912014 0.76 MGLL (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4041393-B1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AG (DE) 2026-04-08 EP disclosed
WO-2025106383-A1 PYRROLIDINYL DERIVATIVES USEFUL AS HCN1/HCN 2 MODULATORS MERCK SHARP & DOHME LLC (US) 2025-05-22 WO disclosed
CN-117567338-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2024-02-20 CN disclosed
US-20230028441-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES ELANCO ANIMAL HEALTH GMBH (DE) 2023-01-26 US disclosed
EP-4041393-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-08-17 EP disclosed
CN-114867529-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2022-08-05 CN disclosed
WO-2021069567-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2021-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230028441-A1 NOVEL HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES PRXL2A, GLRX3, CYP4F3 HPGD 4450/4885RBP4 4067/4885SMO 4846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.