Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.57 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | GSPT1 | P15170 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535151 | 0.86 | CRBN (0.70) | CRBN | |
| SCHEMBL24601235 | 0.79 | CRBN (0.69) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL1413817 | 0.79 | CRBN (0.69) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL29488410 | 0.79 | CRBN (0.69) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL21759475 | 0.78 | CRBN (0.67) | CRBNCSNK1A1 | |
| SCHEMBL30170866 | 0.78 | CRBN (0.67) | CRBNCSNK1A1 | |
| SCHEMBL23534541 | 0.76 | CRBN (0.62) | CRBNIKZF2CSNK1A1GSPT1 | |
| SCHEMBL21759952 | 0.76 | CRBN (0.71) | CRBN | |
| SCHEMBL21760436 | 0.76 | CRBN (0.70) | CRBN | |
| SCHEMBL24046504 | 0.76 | CRBN (0.67) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021069705-A1 | ISOINDOLINONE COMPOUNDS | MONTE ROSA THERAPEUTICS (CH) | 2021-04-15 | — | — | WO | disclosed |