Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2320050 | 0.81 | DEGS1 (0.49) | DEGS1EGLN1NPC1ALDH1A1RAB9A | |
| SCHEMBL2360450 | 0.81 | EGLN1 (0.44) | EGLN1VEGFAFLT1MEN1ALDH1A1 | |
| SCHEMBL2317975 | 0.80 | DEGS1 (0.46) | DEGS1NPC1RAB9ASMN1; SMN2DGAT1 | |
| SCHEMBL2360145 | 0.78 | KDR (0.46) | EGLN1KDRTEKGPR55DGAT1 | |
| SCHEMBL2321384 | 0.77 | DEGS1 (0.41) | DEGS1EGLN1VEGFAFLT1KDR | |
| SCHEMBL2325022 | 0.77 | DEGS1 (0.51) | DEGS1EGLN1NPC1ALDH1A1RAB9A | |
| SCHEMBL2324956 | 0.77 | EPHB4 (0.46) | KDREPHB4TEKMEN1NPC1 | |
| SCHEMBL2359964 | 0.74 | DEGS1 (0.46) | DEGS1KDRTEKKIF11NPC1 | |
| SCHEMBL2320830 | 0.72 | CNR2 (0.44) | EGLN1VEGFAFLT1KDREPHB4 | |
| SCHEMBL2321676 | 0.71 | KIF11 (0.41) | KIF11HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |