Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 7/20 | 0.43 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821129 | 0.86 | PTGS1 (0.53) | DEGS1PTGS1TRPV1NPC1RAB9A | |
| SCHEMBL2360145 | 0.81 | KDR (0.46) | KDRTEK | |
| SCHEMBL2324450 | 0.80 | TEK (0.52) | KIF11CA12CA9TEKNPC1 | |
| SCHEMBL2317975 | 0.80 | DEGS1 (0.46) | DEGS1NPC1RAB9A | |
| SCHEMBL2320050 | 0.78 | DEGS1 (0.49) | DEGS1NPC1RAB9A | |
| SCHEMBL2360450 | 0.78 | EGLN1 (0.44) | RAB9A | |
| SCHEMBL2359971 | 0.77 | KIF11 (0.43) | DEGS1PTGS1KIF11CCR6CA12 | |
| SCHEMBL6235808 | 0.75 | KIF11 (0.65) | KIF11 | |
| SCHEMBL2325022 | 0.74 | DEGS1 (0.51) | DEGS1NPC1RAB9A | |
| SCHEMBL2321380 | 0.74 | DEGS1 (0.44) | DEGS1KIF11KDRTEKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |