SCHEMBL2321384

SCHEMBL2321384

CC(C)c1ccc(-c2ccc(NC=O)nc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 1/20 0.41
KDR P35968 1/20 0.41
EPHB4 P54760 1/20 0.41
TEK Q02763 1/20 0.41
EGLN1 Q9GZT9 2/20 0.41
TYR P14679 1/20 0.39
VEGFA P15692 1/20 0.39
FLT1 P17948 1/20 0.39
KIF11 P52732 1/20 0.38
GPR55 Q9Y2T6 7/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.35
ERN1 O75460 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2360453 0.81 WNT3A (0.42) EPHB4TEKEGLN1VEGFAFLT1
SCHEMBL2320060 0.81 DEGS1 (0.45) DEGS1KDREPHB4TEKEGLN1
SCHEMBL212774 0.80 ACHE (0.45) DEGS1NPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL2360146 0.78 TEK (0.49) KDRTEKGPR55
SCHEMBL2321380 0.77 DEGS1 (0.44) DEGS1KDREPHB4TEKEGLN1
SCHEMBL2325030 0.77 DEGS1 (0.48) DEGS1EGLN1NPC1RAB9AALDH1A1
SCHEMBL2324964 0.77 EPHB4 (0.48) KDREPHB4TEKNPC1RAB9A
SCHEMBL2359971 0.74 KIF11 (0.43) DEGS1KDRTEKKIF11NPC1
SCHEMBL2320835 0.72 FLT1 (0.44) KDREPHB4TEKEGLN1VEGFA
SCHEMBL24072334 0.71 ABL1 (0.40) EPHB4TEKGPR55RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011094890-A1 PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS ARGUSINA INC. (US) 2011-08-11 WO disclosed