Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315170 | 0.92 | MAOB (0.37) | CXCR3LTA4HMAOB | |
| SCHEMBL12433052 | 0.92 | CXCR3 (0.34) | CXCR3LTA4HMAOB | |
| SCHEMBL2316454 | 0.92 | LTA4H (0.33) | LTA4HMAOB | |
| SCHEMBL2319013 | 0.90 | LTA4H (0.32) | LTA4HMAOB | |
| SCHEMBL2313970 | 0.90 | KCNH2 (0.31) | LTA4H | |
| SCHEMBL2314546 | 0.89 | MAOB (0.33) | LTA4HMAOB | |
| SCHEMBL2319020 | 0.89 | HTR7 (0.32) | LTA4HMAOB | |
| SCHEMBL2318162 | 0.89 | LTA4H (0.32) | LTA4HMAOB | |
| SCHEMBL2314928 | 0.88 | MAOB (0.31) | LTA4HMAOB | |
| SCHEMBL2317652 | 0.88 | LTA4H (0.31) | LTA4HMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | claimed |