Hydroxytoluic Acid

Hydroxytoluic Acid

SCHEMBL23214419

CCCC[P+](CCCC)(CCCC)CCCC.Cc1cccc(C(=O)[O-])c1O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KMT2A Q03164 3/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C9 P11712 1/20 0.42
GAA P10253 3/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 2/20 0.38
RXFP1 Q9HBX9 1/20 0.38
USP2 O75604 1/20 0.38
CA2 P00918 1/20 0.38
PLAU P00749 2/20 0.37
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
PLG P00747 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxytoluic Acid SCHEMBL29794311 1.00 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDHSD17B10KMT2A
SCHEMBL23214414 0.85 ALDH1A1 (0.38) ALDH1A1KDM4EHPGDCYP3A4CYP2C9
Phthalic Acid SCHEMBL5048545 0.82 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDKMT2ACYP3A4
Hydroxytoluic Acid SCHEMBL29374776 0.82 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDHSD17B10KMT2A
Hydroxytoluic Acid SCHEMBL31175008 0.81 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A
Hydroxytoluic Acid SCHEMBL9418192 0.81 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A
Hydroxytoluic Acid SCHEMBL29975309 0.81 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A
Hydroxytoluic Acid SCHEMBL622891 0.81 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A
Hydroxytoluic Acid SCHEMBL416477 0.81 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A
Hydroxytoluic Acid SCHEMBL29975592 0.81 ALDH1A1 (0.64) ALDH1A1KDM4EHPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240058452-A1 PHARMACEUTICAL COMPOSITION CONTAINING TEMPERATURE-RESPONSIVE IONIC LIQUID TORAY INDUSTRIES, INC. (JP) 2024-02-22 US disclosed
CN-114502142-B Pharmaceutical composition comprising temperature responsive ionic liquid 东丽株式会社 2023-05-09 CN disclosed
EP-4043007-A1 PHARMACEUTICAL COMPOSITION INCLUDING TEMPERATURE-RESPONSIVE IONIC LIQUID Toray Industries, Inc. (JP) 2022-08-17 EP disclosed
CN-114502142-A Pharmaceutical compositions comprising temperature-responsive ionic liquids 东丽株式会社 2022-05-13 CN disclosed
WO-2021070893-A1 PHARMACEUTICAL COMPOSITION INCLUDING TEMPERATURE-RESPONSIVE IONIC LIQUID 東レ株式会社 2021-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240058452-A1 PHARMACEUTICAL COMPOSITION CONTAINING TEMPERATURE-RESPONSIVE IONIC LIQUID SULT1A1, CYP2C19, SULT2A1 ALDH1A1 1394/4885KDM4E 3065/4885HPGD 3240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.