Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897052 | 0.83 | PPARA (0.62) | MAPTKDM4EMEN1KMT2AJAK2 | |
| SCHEMBL6690265 | 0.77 | PDK1 (0.76) | MAPTKDM4EMEN1KMT2AJAK2 | |
| SCHEMBL4049187 | 0.76 | SMN1; SMN2 (0.61) | MAPTKDM4EMEN1KMT2AJAK2 | |
| SCHEMBL8050339 | 0.76 | RAB9A (0.60) | MAPTKDM4EMEN1KMT2ARAB9A | |
| SCHEMBL8653743 | 0.75 | PPARA (0.59) | MAPTKDM4EMEN1KMT2AJAK2 | |
| SCHEMBL10668694 | 0.75 | PPARA (0.59) | MAPTKDM4EMEN1KMT2AJAK2 | |
| SCHEMBL23214800 | 0.74 | PDK1 (0.51) | MAPTKDM4EMEN1KMT2AJAK2 | |
| SCHEMBL27593568 | 0.72 | SMN1; SMN2 (0.49) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL31294003 | 0.71 | PPARA (0.55) | MAPTKDM4EMEN1KMT2AJAK2 | |
| SCHEMBL6902779 | 0.71 | PDK1 (0.81) | MAPTKDM4EMEN1KMT2AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021070957-A1 | BENZENE CONDENSED RING COMPOUND AND MEDICAL COMPOSITION CONTAINING SAME | 国立大学法人東北大学 | 2021-04-15 | — | — | WO | disclosed |