Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875184 | 0.76 | HCAR2 (0.72) | DAOHCAR2NPC1RAB9AMEN1 | |
| SCHEMBL2319788 | 0.75 | MAPT (0.54) | DAOHCAR2SRD5A2CES1MEN1 | |
| SCHEMBL14637850 | 0.74 | DHODH (0.47) | DHODHDAOHCAR2NPC1RAB9A | |
| SCHEMBL14637852 | 0.74 | DHODH (0.47) | DHODHDAOHCAR2NPC1RAB9A | |
| SCHEMBL30591798 | 0.73 | SRD5A2 (0.51) | SRD5A2CES2CES1NPC1RAB9A | |
| SCHEMBL648641 | 0.72 | SRD5A2 (0.83) | SRD5A2CES2CES1NPC1RAB9A | |
| SCHEMBL9776264 | 0.71 | SRD5A2 (0.68) | SRD5A2CES2CES1NPC1RAB9A | |
| SCHEMBL14044077 | 0.71 | DAO (0.50) | DAOHCAR2NPC1RAB9AMEN1 | |
| SCHEMBL28558518 | 0.70 | SRD5A2 (0.61) | SRD5A2CES2CES1NPC1RAB9A | |
| SCHEMBL15686207 | 0.70 | SRD5A2 (0.61) | SRD5A2CES2CES1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |