Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 12/20 | 0.48 |
| ▸ | TK2 | O00142 | 5/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23215201 | 0.93 | TYMP (0.46) | TYMPTK2 | |
| SCHEMBL23217422 | 0.89 | TYMP (0.58) | TYMPP2RY14P2RY2 | |
| SCHEMBL13714390 | 0.88 | TYMP (0.52) | TYMPTK2 | |
| SCHEMBL13205006 | 0.88 | TYMP (0.52) | TYMPTK2 | |
| SCHEMBL3068344 | 0.88 | TYMP (0.52) | TYMPTK2 | |
| SCHEMBL8535195 | 0.88 | TYMP (0.51) | TYMPTK2P2RY14HSP90AA1 | |
| SCHEMBL8533223 | 0.88 | TYMP (0.51) | TYMPTK2P2RY14HSP90AA1 | |
| SCHEMBL23217006 | 0.84 | TYMP (0.41) | TYMPTK2P2RY14 | |
| SCHEMBL20503186 | 0.84 | TYMP (0.51) | TYMPP2RY14P2RY2 | |
| SCHEMBL17223118 | 0.84 | TYMP (0.51) | TYMPP2RY14P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220384-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-07-13 | — | — | US | disclosed |
| EP-4022059-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | Wave Life Sciences Ltd. (SG) | 2022-07-06 | — | — | EP | disclosed |
| CN-114585737-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2022-06-03 | — | — | CN | disclosed |
| WO-2021071858-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-04-15 | — | — | WO | disclosed |