Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 16/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010123 | 1.00 | NTRK1 (0.52) | NTRK1RPS6KB1JAK2JAK3IGF1R | |
| SCHEMBL4077928 | 0.90 | NTRK1 (0.49) | NTRK1RPS6KB1IGF1R | |
| SCHEMBL4162039 | 0.84 | NTRK1 (0.62) | NTRK1JAK2JAK3IGF1R | |
| SCHEMBL15209597 | 0.84 | PAK1 (0.49) | NTRK1IGF1R | |
| SCHEMBL4072134 | 0.83 | NTRK1 (0.48) | NTRK1JAK2JAK3 | |
| SCHEMBL4071743 | 0.82 | NTRK1 (0.47) | NTRK1JAK2JAK3 | |
| SCHEMBL4074269 | 0.82 | NTRK1 (0.49) | NTRK1JAK2JAK3 | |
| SCHEMBL2511149 | 0.82 | NTRK1 (0.41) | NTRK1JAK2JAK3GPR55 | |
| SCHEMBL4491060 | 0.82 | NTRK1 (0.41) | NTRK1JAK2JAK3GPR55 | |
| SCHEMBL4074195 | 0.76 | NTRK1 (0.69) | NTRK1JAK2JAK3IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072238-A1 | FEEDER-BASED AND FEEDER-FREE STEM CELL CULTURE SYSTEMS FOR STRATIFIED EPITHELIAL STEM CELLS, AND USES RELATED THERETO | UNIVERSITY OF HOUSTON SYSTEM (US) | 2021-04-15 | — | — | WO | disclosed |