SCHEMBL2321732

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19285699	0.77	KDM1A (0.50)	PARP10MAPTLMNAHTT
	SCHEMBL2316902	0.75	AGXT (0.50)	CYP2A6LMNAHTT
	SCHEMBL14777071	0.75	DHFR (0.45)	CYP2A6SMN1; SMN2MEN1KMT2APOLB
	SCHEMBL204282	0.74	NPC1 (0.64)	SMN1; SMN2MEN1KMT2AMAPT
	SCHEMBL2704607	0.74	MRGPRX4 (0.45)	MEN1KMT2AMAOBPARP15PARP14
	SCHEMBL202084	0.74	SLC1A3 (0.41)	MAPK8POLBLMNAHTT
	SCHEMBL201883	0.73	SLC1A3 (0.40)	SMN1; SMN2MEN1KMT2APOLBPARP15
	SCHEMBL12432971	0.72	TNKS2 (0.34)	POLBCA2MAOBPARP15PARP14
	SCHEMBL201521	0.71	PPARD (0.49)	MEN1KMT2APOLBTAAR1MAPT
	SCHEMBL204397	0.71	SMN1; SMN2 (0.50)	SMN1; SMN2MEN1KMT2AMAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.