SCHEMBL204397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2707295	0.91	LMNA (0.51)	LMNAMAPTKDM4EGAASCN9A
	SCHEMBL2707292	0.91	RAB9A (0.46)	SMN1; SMN2LMNARAB9AMAPTKDM4E
	SCHEMBL2706142	0.90	SCN9A (0.53)	LMNASCN9AKCNH2TP53PTGER1
	SCHEMBL2705785	0.89	KDM4E (0.45)	SMN1; SMN2LMNARAB9AMAPTKDM4E
	SCHEMBL204223	0.89	LMNA (0.48)	SMN1; SMN2LMNARAB9AMAPTKDM4E
	SCHEMBL2705819	0.87	ALDH1A1 (0.53)	SMN1; SMN2LMNARAB9AMAPTKDM4E
	SCHEMBL2705780	0.86	SHMT2 (0.50)	LMNAKDM4ESCN9AKCNH2HPGD
	SCHEMBL2705652	0.85	SLC6A4 (0.49)	LMNARAB9AMAPTKDM4ENPC1
	SCHEMBL202844	0.83	MAPT (0.53)	SMN1; SMN2LMNARAB9AMAPTKDM4E
	SCHEMBL2316056	0.82	ALDH1A1 (0.52)	SMN1; SMN2LMNARAB9AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.