Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010252 | 1.00 | TBXAS1 (0.41) | TBXAS1CFDGRM2DUSP3PTPN5 | |
| SCHEMBL23217835 | 0.86 | CFD (0.39) | TBXAS1CFDDUSP3PTPN5PTPN11 | |
| SCHEMBL30010173 | 0.86 | CFD (0.39) | TBXAS1CFDDUSP3PTPN5PTPN11 | |
| SCHEMBL30009755 | 0.85 | CFD (0.51) | TBXAS1CFDGRM2 | |
| SCHEMBL23217854 | 0.85 | CFD (0.51) | TBXAS1CFDGRM2 | |
| SCHEMBL23217842 | 0.84 | KCNA3 (0.41) | TBXAS1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL30010388 | 0.84 | KCNA3 (0.41) | TBXAS1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL23217528 | 0.84 | TBXAS1 (0.41) | TBXAS1CFDDUSP3PTPN5PTPN11 | |
| SCHEMBL29672939 | 0.84 | TBXAS1 (0.41) | TBXAS1CFDDUSP3PTPN5PTPN11 | |
| SCHEMBL30009850 | 0.84 | TBXAS1 (0.41) | TBXAS1CFDDUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |