Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 3/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672939 | 1.00 | TBXAS1 (0.41) | TBXAS1KCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL23217528 | 1.00 | TBXAS1 (0.41) | TBXAS1KCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL30010173 | 0.87 | CFD (0.39) | TBXAS1KCNA3MEN1KMT2ACFD | |
| SCHEMBL23217835 | 0.87 | CFD (0.39) | TBXAS1KCNA3MEN1KMT2ACFD | |
| SCHEMBL30010388 | 0.87 | KCNA3 (0.41) | TBXAS1KCNA3MEN1KMT2ADUSP3 | |
| SCHEMBL23217842 | 0.87 | KCNA3 (0.41) | TBXAS1KCNA3MEN1KMT2ADUSP3 | |
| SCHEMBL23217511 | 0.86 | DUSP3 (0.42) | TBXAS1MEN1KMT2ACFDDUSP3 | |
| SCHEMBL23217521 | 0.85 | CFD (0.50) | TBXAS1CFDPTGER1 | |
| SCHEMBL30009787 | 0.85 | CFD (0.50) | TBXAS1CFDPTGER1 | |
| SCHEMBL23217640 | 0.84 | CFD (0.38) | TBXAS1MEN1KMT2ACFDDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |