Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 5/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F5 | P12259 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30010075 | 1.00 | TBXAS1 (0.37) | TBXAS1CFDROCK1UCHL1L3MBTL1 | |
| SCHEMBL21438522 | 0.89 | NR1H2 (0.34) | TBXAS1CFDTP53HPGDALDH1A1 | |
| SCHEMBL25883833 | 0.86 | FFAR1 (0.33) | UCHL1CXCR2KMT2AMEN1POLB | |
| SCHEMBL21439176 | 0.84 | TBXAS1 (0.38) | TBXAS1CFDUCHL1CXCR2KMT2A | |
| SCHEMBL21438701 | 0.83 | CFD (0.47) | TBXAS1CFDUCHL1POLBPKM | |
| SCHEMBL30010574 | 0.83 | CFD (0.47) | TBXAS1CFDUCHL1POLBPKM | |
| SCHEMBL30010565 | 0.83 | CFD (0.47) | TBXAS1CFDUCHL1POLBPKM | |
| SCHEMBL23217869 | 0.83 | CFD (0.41) | TBXAS1CFDL3MBTL1KMT2ATP53 | |
| SCHEMBL21438656 | 0.83 | CXCR2 (0.32) | UCHL1CXCR2POLBMAOB | |
| SCHEMBL23217749 | 0.83 | MRGPRX4 (0.33) | UCHL1CXCR2POLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555570-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-27 | — | — | CN | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |