Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217501 | 0.91 | UGT2B7 (0.38) | UGT2B7KDM4EMAOACA9 | |
| SCHEMBL23217701 | 0.71 | FFAR1 (0.35) | CA9 | |
| SCHEMBL23217832 | 0.71 | MAOB (0.35) | KDM4EMAOAMAOBCA9 | |
| SCHEMBL3310919 | 0.70 | CYP3A4 (0.42) | UGT2B7KDM4EMAOAMAOB | |
| SCHEMBL23217823 | 0.68 | CA9 (0.35) | KDM4ECA9 | |
| SCHEMBL22042249 | 0.67 | TYR (0.39) | KDM4E | |
| SCHEMBL2463440 | 0.66 | MAOB (0.45) | KDM4EMAOAMAOB | |
| SCHEMBL5987250 | 0.65 | TSHR (0.32) | CA9 | |
| SCHEMBL16426152 | 0.65 | GPR35 (0.37) | PTPN1MAOAMAOB | |
| SCHEMBL31550143 | 0.65 | MAOA (0.36) | KDM4EMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041717-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |