Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217823 | 0.81 | CA9 (0.35) | CA9 | |
| SCHEMBL23217501 | 0.75 | UGT2B7 (0.38) | CA9 | |
| SCHEMBL8770931 | 0.72 | L3MBTL1 (0.37) | — | |
| Hexane SCHEMBL23217895 | 0.71 | PTPN1 (0.33) | CA9 | |
| SCHEMBL23217832 | 0.71 | MAOB (0.35) | KMT2ACA9 | |
| SCHEMBL23217219 | 0.71 | CTNNB1 (0.38) | KMT2AXDHSLC22A12 | |
| SCHEMBL5987785 | 0.70 | TTR (0.47) | KMT2AXDHSLC22A12CA9 | |
| SCHEMBL23217589 | 0.69 | CFD (0.46) | — | |
| SCHEMBL8770980 | 0.69 | SLC22A6 (0.37) | — | |
| SCHEMBL21437695 | 0.67 | RAB9A (0.38) | KMT2AXDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |