Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23217934 | 1.00 | OPRM1 (0.38) | OPRM1MPONPSR1TDP1MAPT | |
| SCHEMBL23225711 | 0.94 | OPRM1 (0.38) | OPRM1MPONPSR1TDP1MAPT | |
| SCHEMBL23217964 | 0.88 | OPRM1 (0.39) | OPRM1MPONPSR1TDP1MAPT | |
| SCHEMBL23217967 | 0.88 | OPRM1 (0.39) | OPRM1MPONPSR1TDP1MAPT | |
| SCHEMBL23225676 | 0.84 | MPO (0.42) | OPRM1MPOMAPTKDM4EALDH1A1 | |
| SCHEMBL27102078 | 0.84 | MPO (0.45) | OPRM1MPONPSR1MAPTMEN1 | |
| SCHEMBL23225713 | 0.83 | OPRM1 (0.39) | OPRM1MPONPSR1TDP1MAPT | |
| SCHEMBL23225710 | 0.83 | OPRM1 (0.39) | OPRM1MPONPSR1TDP1MAPT | |
| SCHEMBL27102019 | 0.82 | MPO (0.43) | OPRM1MPONPSR1MEN1KMT2A | |
| SCHEMBL27141256 | 0.81 | OPRM1 (0.37) | OPRM1MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. | 2024-02-29 | — | — | US | disclosed |
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | MPO, CAT, SOD1 | OPRM1 1161/4885MPO 1/4885NPSR1 1791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.