Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 13/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24312358 | 0.78 | TGFBR1 (0.48) | TGFBR1 | |
| SCHEMBL24312439 | 0.71 | HTT (0.47) | BRD4MAPT | |
| SCHEMBL23217933 | 0.68 | TGFBR1 (0.54) | TGFBR1 | |
| SCHEMBL24311930 | 0.67 | L3MBTL1 (0.43) | BRD4MAPT | |
| SCHEMBL24312357 | 0.66 | TGFBR1 (0.53) | TGFBR1 | |
| SCHEMBL2572901 | 0.65 | SUCNR1 (0.49) | SUCNR1MAPT | |
| SCHEMBL31457839 | 0.65 | MAPT (0.51) | SUCNR1MAPT | |
| SCHEMBL13480435 | 0.64 | MAPT (0.65) | MAPT | |
| SCHEMBL23217905 | 0.63 | CA12 (0.40) | SUCNR1 | |
| SCHEMBL10115818 | 0.63 | MAPT (0.55) | SUCNR1BRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076905-A1 | ALK5 INHIBITORS, CONJUGATES, AND USES THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |
| WO-2021072330-A1 | GALNAC-TGFBR1 INHIBITOR CONJUGATES FOR THE TREATMENT OF LIVER DISEASES | SILVERBACK THERAPEUTICS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |