Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29773056 | 1.00 | CASP3 (0.32) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL31172125 | 0.92 | CASP3 (0.33) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL22636487 | 0.92 | CASP3 (0.33) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL25020373 | 0.88 | CASP3 (0.32) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL28931092 | 0.86 | GBA1 (0.35) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL29867943 | 0.85 | CASP3 (0.32) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL7736866 | 0.85 | CASP3 (0.32) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL17485426 | 0.85 | NPC1 (0.35) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL23698705 | 0.80 | ALDH1A1 (0.35) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL25657190 | 0.79 | GRM5 (0.33) | CASP3SENP8SENP7SENP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041735-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | Biohaven Therapeutics Ltd. (US) | 2022-08-17 | — | — | EP | disclosed |
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |