Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | CFD | P00746 | 3/20 | 0.33 |
| ▸ | F11 | P03951 | 2/20 | 0.33 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29852636 | 1.00 | MTNR1A (0.36) | MTNR1AMTNR1BCFDF11TPSB2 | |
| SCHEMBL29853229 | 0.85 | MTNR1A (0.37) | MTNR1AMTNR1BCFDF11TPSB2 | |
| SCHEMBL23218702 | 0.85 | MTNR1A (0.37) | MTNR1AMTNR1BCFDL3MBTL1ALDH1A1 | |
| SCHEMBL29853074 | 0.85 | MTNR1A (0.37) | MTNR1AMTNR1BCFDL3MBTL1ALDH1A1 | |
| SCHEMBL23219131 | 0.85 | MTNR1A (0.37) | MTNR1AMTNR1BCFDL3MBTL1LMNA | |
| SCHEMBL23218235 | 0.85 | MTNR1A (0.37) | MTNR1AMTNR1BCFDF11TPSB2 | |
| SCHEMBL23218234 | 0.84 | MTNR1A (0.38) | MTNR1AMTNR1BL3MBTL1ALDH1A1LMNA | |
| SCHEMBL23218513 | 0.84 | MTNR1A (0.36) | MTNR1AMTNR1BCFDF11TPSB2 | |
| SCHEMBL23218573 | 0.83 | CFD (0.37) | MTNR1AMTNR1BCFDF11TPSB2 | |
| SCHEMBL29852443 | 0.83 | CFD (0.37) | MTNR1AMTNR1BCFDF11TPSB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502168-A | Oral complement factor D inhibitors | 拜奥克里斯特制药公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |