Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23218702 | 1.00 | MTNR1A (0.37) | MTNR1AMTNR1BL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL29853229 | 0.87 | MTNR1A (0.37) | MTNR1AMTNR1BL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL23218235 | 0.87 | MTNR1A (0.37) | MTNR1AMTNR1BL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL23219131 | 0.87 | MTNR1A (0.37) | MTNR1AMTNR1BL3MBTL1MEN1KMT2A | |
| SCHEMBL29852925 | 0.85 | TBXAS1 (0.38) | MTNR1AMTNR1BL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL23219011 | 0.85 | TBXAS1 (0.38) | MTNR1AMTNR1BL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL23218234 | 0.85 | MTNR1A (0.38) | MTNR1AMTNR1BL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL23218513 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL23218512 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BL3MBTL1ALDH1A1LMNA | |
| SCHEMBL29852636 | 0.85 | MTNR1A (0.36) | MTNR1AMTNR1BL3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041238-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |